AMP-activated protein kinase (AMPK) is a central regulator of energy homeostasis that modulates numerous metabolic pathways. Despite substantial interest in therapeutically targeting AMPK — ...

Adenosine monophosphate (AMP)-activated protein kinase (AMPK) plays an important role in cellular energy homeostasis, helping in growth regulation and metabolic reprogramming in eukaryotes. The AMPK ...

This graphic illustration of a study in Cell Reports shows how a molecular energy regulator in cells, AMPK, is required for astrocytic glycoses, lactate production and lactate shuttle to bio-energize ...

Grahame Hardie received funding from Cancer Research UK for this research. The basic unit of all living things is the cell – and the human body contains tens of trillions of them. Cancer can be ...

Please provide your email address to receive an email when new articles are posted on . Poxel SA announced positive results for the phase 2a trial of PXL770 for the treatment of nonalcoholic ...

Efficient in vitro expression of the human reverse transcriptase (hTERT) but impaired maturation in dendritic cells of lung cancer patients ...

Cancer often results in weight loss due to unwanted metabolic complications. This so-called cancer cachexia is accompanied by a poor prognosis with regard to disease progression, quality of life, and ...

Most breast cancers utilize the female hormone estrogen to grow, so drug-induced estrogen deprivation is used as a treatment in many patients. However, cancer will recur in one-third of these patients ...

Mystery of the contradicting abilities of the AMPK enzyme in cancer growth finally solved. Genetically engineered lung tumors – solid purple. Credit: Salk Institute. Previously thought to suppress ...

Metabasis Therapeutics, Inc. has announced an extension to the sponsored research term under its collaboration with Merck & Co., Inc. for an additional year, through June 2009. The two companies will ...