Early in the pandemic, most research, including our own, focused on designing drugs that could block the virus's spike protein. This was a logical first step, but as we've seen, the virus is a moving ...

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors. Blocking this interaction with inhibitors could prevent ...

Researchers have identified new host factors that interact with the receptor binding domain of the SARS-CoV-2 spike protein to promote viral entry. This finding offers valuable mechanistic insights ...

SARS-CoV-2, the virus responsible for COVID-19, infects cells by binding its spike protein to angiotensin-converting enzyme 2 (ACE2) receptors. Blocking this interaction with inhibitors could prevent ...

Camelid single-domain antibodies, also known as nanobodies, can be readily isolated from naïve libraries for specific targets but often bind too weakly to their targets to be immediately useful.

Coronaviruses have already caused three major disease outbreaks, including the Covid-19 pandemic that hit most countries in the world. However, scientists claim that those pathogens are difficult to ...

New study reveals how lingering spike protein in the brain's borders could explain long-term COVID-19 neurological symptoms and highlight vaccines' protective role. Study: Persistence of spike protein ...

Viruses closely related to the deadly MERS coronavirus are lurking in bats and one group, known as HKU5, may be just one mutation away from making the jump to humans. A new study reveals how these ...