At 12 weeks, a combination pill containing candesartan cilexetil, amlodipine, and chlorthalidone improved BP in patients with hypertension.

Objective: The aim of this study was to compare the antihypertensive efficacy and tolerability of the calcium channel antagonist amlodipine besylate versus the angiotensin II type 1 receptor ...

Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window CHICAGO -- A ...

Eight-week-old male Wistar-Kyoto (WKY) rats and SHR-SP were obtained from Japan SLC (Shizuoka, Japan). All rats were given normal rat chow (F-2, Funabashi Farm, Chiba, Japan). The experiments were ...

The present study was a multicentre, prospective, randomized, open and blinded end-point trial to assess the renoprotective effects of titrating the dose of an ARB, namely candesartan, and combined ...

Candesartan has a greater effect on reducing the risk of new-onset diabetes in patients with hypertension compared with amlodipine, but the calcium channel blocker may have the greater effect in obese ...

Of the 398 patients who entered the placebo washout phase, 326 patients were found to be suit- able for study enrolment and were therefore randomised to double-blind treatment (165 to amlodipine and ...