Signal transduction The cellular process that converts a signal, such as a hormone, growth factor, neurotransmitter, cytokine, mechanical force, or environmental cue, into biochemical changes inside ...

Signal transduction in Saccharomyces cerevisiae orchestrates cellular responses to environmental cues via conserved modules. The pheromone response pathway uses G-protein-coupled receptors to activate ...

Bottom-up construction of artificial cells helps elucidate the working mechanism of cells. Signal transduction from extracellular to intracellular artificial cells is essential for autonomous ...

cases an external molecule dramatically affects cellular function. Our goal in studying any of these processes is the same: a molecule-by-molecule accounting of information transfer in biological ...

A signaling system known as the Wnt pathway plays a central role in how cells in the intestine grow, divide and renew themselves. Decades of research have shown that disruption of this pathway is a ...

Microtubules perform an active role in communication within the cell by transmitting received signals to the cell's functional units. Researchers at the Paul Scherrer Institute PSI and the Department ...

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular ...

An international study led by a scientist at the University of Ottawa Faculty of Medicine is opening new frontiers in the ...

Efficient T-cell engineering is crucial for the success of CAR T-cell therapy research, but it requires multiple labor-intensive steps, including T-cell isolation, activation, and transduction.

That’s gene editing. On paper, it is merely the rearrangement of letters. However, the road to editing genes in hopes of a therapeutic benefit is difficult to travel. Additionally, researchers want ...

Using patient-derived cardiac tissue and stem cell-based models, the team of translational researchers demonstrated that ...