Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

When considering the drugs most likely to cause former addicts to repeatedly relapse, opioids, cocaine, and methamphetamine ...

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Drug addiction is a chronic, often relapsing disorder that affects millions of people worldwide. Despite successful treatment, many individuals struggle to maintain sobriety and may relapse.

Addiction is not simply a chronic brain disease and considering it as such can limit treatment options and increase stigma, an extensive research review suggests. After decades of research, Professor ...

This is a time where we can recognize and celebrate the more than 23 million Americans living in Recovery from a substance use disorder. As a society, it is vital that we understand the impact that ...

PHILADELPHIA, PA — Researchers at Temple University Lewis Katz School of Medicine say a little-known compound could mark a major turning point in the fight against opioid addiction, showing promise in ...

Addiction often isn’t about chasing pleasure—it’s about escaping pain. Researchers at Scripps Research have discovered that a tiny brain region called the paraventricular nucleus of the thalamus (PVT) ...

Relapse prevention is why most people seek treatment, and with opioid use disorders (OUDs), there’s about a 90 percent relapse rate. This article explains why and how specific sayings from self-help ...