A laser (purple) is powerfully amplified by highly polished mirrors and focused on the electron beam (blue) to shift its phase and increase the cryo-EM microscope’s contrast, allowing biologists to ...

Stanford researchers developed the label-free iISM microscope, which can observe structures inside living cells in real time ...

A microscope born in post-war JapanThis time, I am introducing an old Olympus biological microscope, the UCE model ...

The invention that first enabled researchers to see clear images of living cells was the phase-contrast microscope, which won its inventor, Frits Zernike, a Nobel Prize in 1932. Prior to Zernike's ...

Light sheet microscopy allows biologists to selectively light up a thin slice of a sample. This method can improve image ...

Researchers at Rice University have developed 3D-nanoprinted reflective micromirror inserts that enable single-objective ...

Electron microscopy is a powerful technique that provides high-resolution images by focusing a beam of electrons to reveal fine structural details in biological and material specimens. 2 Because ...