Psilocybin, LSD, mescaline, DMT, and ayahuasca have different chemical structures, different durations, different cultural histories - and they all do the same thing to the brain. A mega-analysis ...

New research suggests that a single dose of the psychedelic compound DMT can reverse symptoms of depression, including loss of pleasure and cognitive decline, in mice subjected to chronic stress. The ...

To learn more about our editorial approach, explore The Direct Message methodology. Carla Mendes, a 34-year-old graphic designer in Bristol, had been on antidepressants for eleven years when she sat ...

The team also concludes that what emerges is a brain that is not merely disordered under psychedelics, but reorganized. Its ...