Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.

The epigenetic modification, DNA methylation, is characterized by 5-methylcytosine (5-mC) and found in specific genomic locations, most notably regulatory regions such as promoters and enhancers.

Blood tests have proved to be a promising tool for detecting and monitoring cancer. Researchers at Chalmers University of Technology and the University of Gothenburg, Sweden, have now developed a new ...

PCR genetic analysis has been in the spotlight since COVID-19, but light is now further facilitating PCR-free methods. Osaka Metropolitan University scientists have developed a light-induced DNA ...

Quantitative polymerase chain reaction (qPCR) is a molecular technique that has reshaped the landscape of biological research and medicine due to its high sensitivity and specificity. qPCR, also known ...

Repeats of DNA sequences, often referred to as 'junk DNA' or 'dark matter,' that are found in chromosomes and could contribute to cancer or other diseases have been challenging to identify and ...

Emerging methods are improving the ability to identify even highly degraded human remains. By Damien Cave Reporting from Hanoi, Vietnam The world is facing an abundance of tragic events that produce ...

Researchers using cutting-edge environmental DNA (eDNA) technology have uncovered far greater biodiversity in eastern Ontario waterways than traditional monitoring methods detected over more than a ...