Astrocytic GLUR5 and dopamine D1 signaling. Illustration showing that astrocytically expressed GLUR5 and dopamine D1R and their coupled Ca 2+ signaling triggers the release of astrocytic factors (e.g.

Ms. Szalavitz is a contributing Opinion writer who covers addiction and public policy. In late 2016, Steven Klein realized that he’d lost control over his drinking and stimulant use. He became sober ...

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

Ms. Szalavitz is a contributing Opinion writer. Jessica Massarone couldn’t concentrate in primary school: She was too preoccupied with her parents’ struggles with drug addiction. Sometimes, she’d find ...

Manila: Jessie Carlos, a former Department of Finance employee with a rank of “Tax Specialist I”, accumulated $81,000 (about ₱5 million) in gambling debts. That drove berserk: He opened fire at casino ...

MIAMI — When Susan Akin first started injecting a coveted weight-loss drug early this year, the chaos in her brain quieted. The relentless cravings subsided — only they’d never been for food. The ...

Research published in high-quality peer-reviewed journals reveals key information on the realities of addiction, exposing pervasive myths and misconceptions, as in these examples. False Belief 1: Drug ...