Reversing fibrosis: New research provides insight for novel therapies

Yale School of Medicine (YSM) researchers have made key breakthroughs in understanding how to treat fibrotic diseases such as ...
EMBO Press

circ-EGFR is a predictor of response to Cetuximab and a potential target in colorectal cancer

Circ-EGFR was identified as a novel predictive biomarker for cetuximab efficacy in KRAS wild-type metastatic colorectal ...
Healio

Pathophysiology and Molecular Pathways

Human epidermal growth factor receptor 2 (HER2) is a membrane-spanning receptor that belongs to the family of epidermal growth factor receptor tyrosine kinases (EGFR TKIs), which consists of three ...

Sangamo targets Q1 2026 BLA submission for Fabry gene therapy as FDA affirms accelerated pathway

Q3 2025 Management View CEO Alexander Macrae highlighted continued advancement of the clinical and preclinical pipeline, with a focus on managing cash resources. Macrae stated, "In September, we ...

New Pooled 3-Year Analysis Confirms Sustained, Clinically Meaningful Improvements in Renal Function for TransCon® PTH (Palopegteriparatide)-Treated Adults with Hypoparathyroidism

In both trials, TransCon PTH was generally well tolerated, with no new safety signals identified. Most treatment-emergent adverse events (TEAEs) were mild to moderate (Grade 1 or 2) and no patients ...