Development of MDCK and ELT3 cell lines with stable expression of tuberin To determine whether other members of the Rho family were also activated, we studied Rac1 and cdc42 using a Pak1-p21 binding ...
Tuberous sclerosis complex (TSC) is an autosomally inherited disorder with benign tumor formation in the brain, kidney, heart, lung, skin and eye (Cheadle et al., 2000; Dabora et al., 2001). The most ...