Materials scientists have extensively studied fast ion permeation in nanofluidic channels in the past decades due to their potential within filtration technologies and osmotic energy harvesting. While ...

The ion channel PIEZO2 doesn't just convey touch stimuli. It also plays a key role in the development of coronary vessels, a team led by Annette Hammes from the Max Delbrück Center reports in Nature ...

In the early 1980s, scientists observed an anomaly. Embedded within cell membranes, they identified ion channels with ...

Ion channels regulate the selective flow of ions across cellular membranes, underpinning the electrical signalling that drives cardiac rhythm and modulating pathways that control cell proliferation, ...

A mouse study finds that the KCNE3-KCNQ1 potassium channel axis couples mitochondrial energy metabolism to vessel growth and ...

A new study in mice and cardiomyocytes shows that TRPM7 promotes ischemia-reperfusion heart injury through a ...

Ion channels are attractive drug targets due to their importance in health and disease, but finding ways to target a specific ion channel selectively is a major challenge. Now, researchers have ...

A member of an important class of ion channel proteins can transiently rearrange itself into a larger structure with dramatically altered properties, according to a new study. The discovery is a ...

Lysosomes are the recycling centers of human cells. Larger molecules are broken down inside the membrane-enclosed vesicles. Malfunctions can lead to neurodegenerative diseases such as Parkinson's.

Researchers have discovered how an ion channel in the brain's neurons has a kind of 'molecular memory', which contributes to the formation and preservation of lifelong memories. The researchers have ...