The glutamate-induced excitotoxicity pathway has been reported in several neurodegenerative diseases. Molecules that inhibit the release of glutamate or cause the overactivation of glutamate receptors ...

Researchers identify JNK kinase as a key host factor driving coronavirus replication, revealing a potential antiviral target.

A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the ...

Doxorubicin (DOX) is widely used to treat cancer but can cause severe heart damage. In a recent study, researchers from China ...

Morphologic and genomic characterization of circulating tumor cells in patients with metastatic colorectal cancer treated with combinational treatment of andecaliximab, bevacizumab and chemotherapy.

Sirtuin 3 (Sirt3)-modified mitochondrial fission participates in the progression of several types of cancers. However, its role in tongue cancer requires investigation. The aim of our study is to ...

Relationship of the oncogene Notch and CXCR4/SDF1 signaling in human epithelial ovarian cancer.

Olfactory ensheathing glia (OEG) play an important role in regulating the regeneration of an injured nervous system. However, chronic inflammation damage reduces the viability of OEG via poorly ...

The discovery could serve as a starting point for antiviral strategies. A research team at Ruhr University Bochum, Germany, ...

A study led by Garvan researchers has uncovered why some breast cancers become resistant to treatment, potentially opening the door to more effective therapies for patients. Published today in the ...

A team of scientists at the Garvan Institute of Medical Research has discovered that inactivation of a stress pathway makes ER+ breast cancer cells ignore stress signals, allowing them to evade ...