PKD is mainly caused by mutations in the PKD1 and PKD2 genes, affecting polycystin proteins. Disrupted signaling pathways, like cAMP and vasopressin, are major drivers of cyst growth. Tolvaptan is ...

Acquired cystic kidney disease represents a condition where fluid-filled sacs (also known as renal cysts) develop in the kidney. These cysts tend to develop in the cortex and medulla regions of the ...

Polycystic kidney disease (PKD) is a genetic disorder marked by the growth of many fluid-filled sacs (cysts) in your kidneys. These cysts can grow to replace normal kidney tissue over time, leading to ...

Using two drugs was no more effective than a single drug in slowing disease progression in people with autosomal dominant polycystic kidney disease (ADPKD), according to two studies. One of the ...

Their results indicated that deletion of the binding site increased stability of the mRNA strand, raised Polycystin-1 levels, and decreased kidney cyst growth. Moreover, the group found that blocking ...

People with polycystic kidney disease (PKD) could benefit from a moderate increase in water intake, according to new research. People with polycystic kidney disease (PKD) could benefit from a moderate ...

Left kidney pain may feel sharp or dull. You may also have pain in your upper back or your stomach. It can be caused by different things that may not be related to your kidneys. Share on Pinterest ...

Kidney cancer is moderately common, the sixth-most prevalent cancer diagnosis for men and women. Benjamin L. Maughan, MD, PharmD, assistant professor in the division of medical oncology, answers ...