Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 24 (June 16, 2020), pp. 13437-13446 (10 pages) Pentameric ligand-gated ion channels (pLGICs) are ...

The process of expressing a wide variety of voltage-gated and ligand-gated ion channels enables nociceptors to transduce receptor potential into single action potentials or multiple action potentials.

This is a preview. Log in through your library . Abstract The current understanding about ethanol effects on the ligand-gated ion channel (LGIC) superfamily has been restricted to identify potential ...

Instrument Seeks to Advance Ligand-Gated Aspect of Critically Important Field The first decade of the 21st century has delivered an extraordinary range of new technologies with relevance to ...

postsynaptic nAChRs mediate skeletal muscle contraction at the neuromuscular junction; ganglionic nAChRs are responsible for fast excitatory transmission in the autonomic nervous system; as well as ...

This is a 3-D computer model of the serotonin 5-HT3 receptor, embedded through a lipid bilayer membrane (horizontal structure with black lines and yellow balls) as it would be naturally in a cell.

For the first time, researchers have learned at the molecular level how the P2X7 protein receptor - which is associated with inflammation, coronary artery disease, cancer, multiple sclerosis and more ...

Touching Base is the dynamic podcast series from the editors of GEN. Each episode features a rotating case of senior editors—including John Sterling, Kevin Davies, Julianna LeMieux, Alex Phillippidis, ...