Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

Scientists have published a ground-breaking study of the structure and function of a central protein in the liver: NTCP, a cellular-entry pathway for bile salts, but also for certain hepatitis viruses ...

If scientists could shrink themselves to microscopic size and take a journey through the human body—like the submarine crew in the 1966 science fiction classic "Fantastic Voyage"—one of their first ...

New genetic map of the human liver reveals why certain areas are more susceptible to fatty liver disease while others are ...

The liver produces bile, which the intestine uses for digestion. For the transport of bile, the liver relies on a network of microscopic tubings, known as bile canaliculi, formed by liver cells called ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

The liver is the only internal organ that can regenerate itself. Remarkably, even if 70 percent of the liver is removed, its tissue can regrow into a full-sized organ within a matter of months. By ...

As seen by the naked eye, the liver has four lobes: right lobe, left lobe, caudate lobe, and quadrate lobe. This lobe division is based on surface features. When looking at the front of the liver, the ...

A liver ultrasound is a noninvasive test a doctor orders to examine the liver, its blood vessels, and sometimes the gallbladder. Abnormal results may indicate a person has liver disease or signal an ...

Though an essential gateway to the liver, NTCP had not been well described until now. Na+-taurocholate co-transporting polypeptide (NTCP) is a protein located exclusively in the membrane of liver ...