M1 and M2 are activated macrophages that protect our immune system and maintain homeostasis. Interestingly, they are characterized by distinct and opposing phenotypes. M1 macrophages are known for ...

The research was led by Prof. Fuping Zhang from the Institute of Microbiology, Chinese Academy of Sciences, in collaboration with Prof. Jian Song from the Guangxi Zhuang Autonomous Region People's ...

First-in-class dendritic cell (DC) maturation agent Plinabulin drives immune re-sensitization in metastatic NSCLC ...

By combining microscopy with machine learning, the team found that a specific phenotype of macrophage was better at traveling to the tumor than others - and it's not the one that researchers commonly ...

Metabolic dysfunction-associated fatty liver disease (MAFLD) has emerged as a predominant chronic liver condition globally, ...

Macrophages serve as the Swiss army knives of the innate immune system, switching between phenotypes to perform different functions in response to the surrounding environment. One of their key ...

Macrophages, a type of white blood cell that can destroy invading pathogens, have an innate ability to infiltrate tumor cells, making them a potentially important tool for cell therapy but so far, ...

Researchers developed and validated a label-free, non-invasive method combining AFM with deep learning for accurate profiling of human macrophage mechanophenotypes and rapid identification of their ...