With multiple, complex chromatographic purification, buffer exchange, and viral inactivation steps, downstream processing of monoclonal antibodies (mAbs) remains the major bottleneck in ...

In the development of end-to-end large-scale live virus vaccine (LVV) manufacturing, process analytical technology (PAT) tools enable timely monitoring of critical process parameters (CPP) and ...

Optimizing the downstream process for adeno-associated virus (AAV) production with consistent quality depends on the ability to characterize critical quality attributes affecting the final product’s ...

Upstream titers of 3–5 g/L, and up to 10–13 g/L, are outpacing downstream capacity, creating chromatography, filtration, and UF/DF throughput bottlenecks that elevate cost and delay timelines. Complex ...

Dublin, May 21, 2026 (GLOBE NEWSWIRE) -- The "Upstream and Downstream Manufacturing in the Biopharmaceutical Industry (June 11, 2026)" training has been added to ResearchAndMarkets.com's offering.

With the recent FDA approval of the CAR T-cell therapies Kymriah ® from Novartis and Yescarta ® from Kite Pharma, there has been a renewed interest in bioprocessing and the manufacturing facilities ...

Drug firms looking to ramp-up production with continuous processes must think beyond the reactor and ensure the technologies used downstream can also manage sustained 24/7 manufacturing. Continuous ...

Drug development and manufacturing have undergone a seismic shift in the last two decades, 1 from blockbuster small molecules to highly personalized biologics 2 and cell and gene therapies. Because ...

Acquisition expands Siemens' offering in PCB design for the SMB market and enables greater process coverage, from design to manufacturing preparation PLANO, Texas, April 8, 2025 /PRNewswire/ -- ...

Fundamental shifts in the supply chain raise important question about how U.S. module manufacturers will be funded in the ...