A rapid multidisciplinary approach is needed to reduce serum free light chain levels and restore kidney function ...

Precancerous, or smoldering, multiple myeloma (SMM) is by definition an asymptomatic disease, and about 50% of those diagnosed with this precursor condition will develop full MM within 5 years.

Multiple myeloma is a cancer of plasma cells, the antibody-making white blood cells that live in your bone marrow. When these cells turn abnormal and multiply, they crowd out healthy blood-forming ...

Identifying low-abundance monoclonal antibodies within a population of polyclonal antibodies provides insights for various applications, including understanding disease mechanisms, vaccine development ...

Smoldering multiple myeloma (SMM) is a precancerous condition affecting white blood cells, called plasma cells, in the bone marrow. It can turn into multiple myeloma, a form of blood cancer that can ...

The disposition of immunoglobulins (IgGs) is influenced by target-dependent and target-independent mechanisms. Target-independent clearance (CLind) of monoclonal antibodies (mAbs) is primarily ...

The Food and Drug Administration has approved more than 100 monoclonal antibodies to treat a range of diseases. Other antibodies are used by physicians to diagnose conditions or by scientists to ...