Oligodendrocytes are specialized cells that confer neuronal myelination in the central nervous system. Leukodystrophies associated with oligodendrocyte deficits and hypomyelination are known to result ...

Oligodendrocytes, the myelinating glia of the central nervous system, contribute fundamentally to axonal insulation, metabolic support and rapid nerve conduction. Emerging evidence implicates ...

How oligodendrocytes use fatty acid metabolism as an energy reserve to maintain axonal function and myelin stability when glucose is scarce, offering insights into neurodegenerative disease mechanisms ...

About half of adult human brain volume is made up of white matter. Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons to form the major components of white ...

To rapidly transmit electrical signals in the brain, the long nerve fibers are insulated by specialized cells called oligodendrocytes. These cells also respond to the electrical signals of active ...

The human brain has about as many neurons as glial cells. These are divided into four major groups: the microglia, the astrocytes, the NG2 glial cells, and the oligodendrocytes. Oligodendrocytes ...

New research for the first time reveals the function of a little-understood junction between cells in the brain that could have important treatment implications for conditions ranging from multiple ...

Multiple sclerosis is a condition whereby the immune system attacks and destroys myelin – the protective coating of nerve fibers – which triggers movement problems characteristic of the disease. Now, ...

Nerve fibers in the brain and spinal cord are wrapped in an insulating sheath known as myelin. For a long time, this barrier, which is essentially the brain's white matter, was believed to serve the ...

Myelin sheaths are critical for efficient signal transmission along axons. Their inactivation could explain some of the neuropathological deficits associated with schizophrenia. In the April 10 ...

While the vast majority of myelin sheaths in the brain are laid down early in life, a pair of new studies published February 10 in Nature Neuroscience reveal that a fresh supply of the fatty axonal ...

More than half amount in adult human brain is made up of white matter. Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons to form the major components of white ...