Oligodendrocytes, the myelinating glia of the central nervous system, contribute fundamentally to axonal insulation, metabolic support and rapid nerve conduction. Emerging evidence implicates ...

About half of adult human brain volume is made up of white matter. Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons to form the major components of white ...

To rapidly transmit electrical signals in the brain, the long nerve fibers are insulated by specialized cells called oligodendrocytes. These cells also respond to the electrical signals of active ...

The human brain has about as many neurons as glial cells. These are divided into four major groups: the microglia, the astrocytes, the NG2 glial cells, and the oligodendrocytes. Oligodendrocytes ...

A new study shows metformin enhances myelin repair in human-based models by tuning mitochondrial metabolism, offering hope for multiple sclerosis treatment. Study: Metformin alters ...

Until recently, oligodendrocytes were primarily thought to be a kind of cellular insulating tape that accelerates the transmission of electrical signals in the brain. A study now shows that they are ...

Nerve fibers in the brain and spinal cord are wrapped in an insulating sheath known as myelin. For a long time, this barrier, which is essentially the brain's white matter, was believed to serve the ...

Multiple sclerosis is a condition whereby the immune system attacks and destroys myelin – the protective coating of nerve fibers – which triggers movement problems characteristic of the disease. Now, ...

Researchers headed by a team at Johns Hopkins School of Medicine have used 3D imaging, special microscopes, and artificial intelligence (AI) to construct maps that show the precise location of more ...

Myelin sheaths are critical for efficient signal transmission along axons. Their inactivation could explain some of the neuropathological deficits associated with schizophrenia. In the April 10 ...

More than half amount in adult human brain is made up of white matter. Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons to form the major components of white ...