Osteopetrosis is a genetic condition of increased bone mass, which is caused by defects in osteoclast formation and function. Both autosomal recessive and autosomal dominant forms exist, but this ...

Background Osteopetrosis is a rare, inherited, bone disorder, characterized by osteosclerosis, obliteration of the medullary cavity and calcified cartilage. The autosomal dominant form is compatible ...

Osteopetrosis can cause a number of serious, potentially life-threatening problems throughout the body. According to the US's National Institute of Arthritis and Musculoskeletal and Skin Diseases ...

Osteopetrosis is an inherited disorder whereby bones harden and become denser. There are several different types of osteopetrosis caused by distinct genetic mutations, but not all the causative ...

A 12-year-old white boy, referred to us for unexplained skeletal pains and markedly elevated serum alkaline phosphatase activity, first began to limp as a result of left-hip discomfort after ...

Malignant Infantile Osteopetrosis (MIOP) is a rare genetic disorder causing excessive bone density, leading to brittle bones, bone marrow failure, and neurological issues. It results from mutations in ...

Severe hypercalcemia developed in both patients within 12 days after HSCT. Serum parathyroid hormone levels were suppressed, and renal ultrasonography showed nephrocalcinosis. Alkaline diuresis and ...

CLINCH COUNTY, Ga. (WALB) - Avery and Mollie James welcomed their first child four months ago. They had no idea that their son, Talon, would be diagnosed with autosomal recessive osteopetrosis at just ...

Fractures typically occur in the appendicular skeleton, most commonly in the proximal femur, [5,20,21] as well as in the femoral shaft, tibia, and upper extremities. [3] These fractures may result ...