Researchers have mapped the 3D organization of genetic material of key developmental stages of human retinal formation, using intricate models of a retina grown in the lab. The findings lay a ...

Scientists at St. Jude Children’s Research Hospital studied the Vsx2 super-enhancer and its role in the development of the retina. Their assessment showed the super-enhancer has four distinct regions ...

Over the last decade, experiments addressing thyroid hormone's role in the retina have generated a sizeable body of data. They have also inspired many more questions that will no doubt be tested in ...

Researchers have identified a gene that is crucial for the proper development of photoreceptor cells in the retina. The gene works by regulating microexons, tiny fragments of DNA that play an ...

During retinal development, Setd8 safeguards chromatin accessibility through the histone marker H4K20me1. When Setd8 is present (right), genes required for retinal progenitor cell maintenance and DNA ...

This study is led by prof. Jin (Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University). For the last decade, he always works on the ...

National Eye Institute (NEI) scientists have found that the way the retina metabolizes glucose directly controls which genes get switched on and off in light-sensing photoreceptors. The findings ...

Enhancers are regions of DNA that do not code for proteins, but control how genes are expressed. Super-enhancers are clusters of enhancers that together regulate genes with important roles in cell ...

This image metaphorically captures the cell differentiation process during retinal organoid development. Loose yarn representing uncompacted DNA is wound by a crochet hook around buttons representing ...