Parkinson's disease causes both movement and cognitive deficits, and for a long time both were thought to be caused by the accumulation of a protein called alpha-synuclein in the brain. But a new ...

The reduction of α-synuclein, which is central to the pathogenesis of Parkinson’s disease and other α-synucleinopathies, can be accomplished through the binding and selective degradation of its ...

Vanda Pharmaceuticals Inc. presented data this week at the annual American Academy of Neurology conference regarding allele-specific antisense oligonucleotides (ASOs) that specifically target the ...