Because synapses are responsible for passing information between neurons, these connections are vital for communication within and outside the brain. Therefore, understanding how they form, function, ...

Clinical portfolio, informed by deep and novel synapse biology and pharmacology insights, aims to strengthen neural connections through event-driven pharmacology Lead candidate zelquistinel is ...

Johns Hopkins scientists reveal that “inactive” GluD brain proteins regulate neuronal communication and open up new ...

The ability to regrow lost synapses can be life changing; for Derek Small, cofounder and CEO of the start-up Syndeio Biosciences, it holds personal relevance. Around a decade ago, Small watched his ...

As we age, we begin to lose the connections that wire up our brains-and neuroscientists aren't sure why.

Alzheimer’s may destroy memory by flipping a single molecular switch that tells neurons to prune their own connections. Researchers found that both amyloid beta and inflammation converge on the same ...

Vesicle recycling in the presynaptic terminal at one end of a neuron, showing the role of dynamin during the last step of endocytosis (membrane retrieval), where the protein cuts off the vesicle from ...

While probing the escape reflex in the fruit fly Drosophila, researchers at Johannes Gutenberg-University Mainz (JGU) and the ...