So far, immune cells that have been engineered to kill cancers, known as CAR T-cells, haven’t worked well against solid ...

Triple-negative breast cancer is one of the most aggressive cancers. The name tells the story: It lacks the three main ...

Chimeric antigen receptor (CAR) T cell therapy, which uses a patient's own immune cells to fight cancer, has emerged as a powerful way to treat lymphoma and other blood cancers. But researchers have ...

Nobel laureate Shimon Sakaguchi reflects on the role of regulatory T cells in peripheral immune tolerance and how the cells ...

MIT and Harvard scientists have designed an advanced type of immune cell called a CAR-NK cell that can destroy cancer while ...

Acute myeloid leukemia (AML) cells under the microscope, in purple. There is a serious need for finding better ways to treat AML that comes back after initial treatment. Chimeric antigen receptor (CAR ...

MIT and Harvard scientists have created engineered CAR-NK cells that can hide from the immune system and more effectively destroy cancer. The cells are designed to suppress immune-rejection signals ...

Killer immune cells destroy cancer cells and cells infected by virus. These CD8 + T cells are activated after detection of viral infection or growth of “non-self” tumor cells. However, in chronic ...

China Medical University leads a multi-institution team reporting that MTAP deficiency suppresses cytosolic nucleic acid ...

Scientists have found a new way to stop cancer growth without damaging healthy cells. Researchers from the Francis Crick ...

The nanoparticle vaccine allowed the mice’s immune system to produce T cells, white blood cells crucial for fighting ...