Northwestern Medicine scientists have identified the cellular mechanisms that cause immune cells to differentiate and ...

In an experimental trial, a personalized mRNA vaccine was tested in 14 individuals with an aggressive form of breast cancer. It trained immune cells to target cancer-specific mutant proteins, inducing ...

A unique quality of the immune system is that it can generate a ‘memory’ response. This is generally referred to as ‘immune ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

SLAMF6 is an immune cell receptor whose function was not clear. Does it activate or inhibit cells? The results so far have been contradictory. Now, scientists at the Institut de Recherches Cliniques ...

Explore the evolution of T-cell engagers, from experimental concepts to effective therapies for haematologic malignancies.

Immunotherapy has transformed cancer care, offering a way to harness the body’s own immune system to fight tumors. But even with these advances, many patients still don’t respond. One major barrier to ...

Immune checkpoint inhibitors (ICIs) are a form of immunotherapy that activates anti-tumor immune cells. In the context of ...