Head coach Kyle Shanahan told reporters at a Monday press conference that running back Isaac Guerendo is going to miss will ...

Discover the top breakout running backs for 2025 fantasy football drafts, including Jordan Mason, Isaac Guerendo, and Omarion ...

The San Francisco 49ers signed running back Ke’Shawn Vaughn to a one-year deal ahead of their first preseason game against the Denver Broncos. Vaughn signed with the 49ers’ practice squad in August ...

Stats and projections for Isaac Guerendo in fantasy football, including ADP, insights, and 2025 outlook, as the San Francisco ...

Injuries forced running back Isaac Guerendo and fullback Kyle Juszczyk out of Saturday’s practice at 49ers training camp.

The 49ers scored a touchdown on their opening series of the preseason, then their defense crumbled in a 30-9 loss against the ...

The preseason is always about depth players being able to find roster spots or starting jobs by showing how well they perform ...

San Francisco 49ers running back Jordan James did not suit up for the 49ers joint practice with the Denver Broncos. The ...

McCaffrey is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report. With Isaac Guerendo ...

Isaac Guerendo ’s mother, Jen, realized that early on. She remembers a family gathering at a park in southern Indiana during which the kids had a big race. Isaac was 5 or 6 at the time.

Last year, the San Francisco 49ers saw their skill-position corps decimated by injuries. Star running back Christian ...