High-intensity focused ultrasound (HIFU) is an increasingly used, locally ablative therapy option in localized prostate cancer (PCa). Multiparametric MRI (mpMRI) is currently used for tumor ...

Treatment-induced neuroendocrine prostate cancer (NEPC) is a lethal subtype of castration-resistant prostate cancer. Using the 89Zr-labeled delta-like ligand 3 (DLL3) targeting antibody SC16 ...

To quantify the aggregation of brain amyloid-β (Aβ) in vivo, different Aβ tracers have been developed for PET imaging techniques, with both clinical and research applications. Aβ PET scans can be ...

Journal of Nuclear Medicine November 2025, jnumed.125.270710; DOI: https://doi.org/10.2967/jnumed.125.270710 ...

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Journal of Nuclear Medicine November 2025, jnumed.125.270568; DOI: https://doi.org/10.2967/jnumed.125.270568 ...

Hybrid PET/MR imaging has recently emerged as a new modality enabling simultaneous molecular and morphologic assessment of a variety of physiopathologic conditions (1). Over the last 2 decades, PET/MR ...

The deployment of artificial intelligence (AI) has the potential to make nuclear medicine and medical imaging faster, cheaper, and both more effective and more accessible. This is possible, however, ...

Amyloid-β (Aβ) accumulation in the brain is a pathologic indicator of Alzheimer disease (AD) that can be imaged using PET. Second-generation PET radiotracers, such as [18 F]florbetaben, [18 ...

Most well-differentiated neuroendocrine tumors (NETs) express high levels of somatostatin receptors, particularly subtypes 2 and 5. Somatostatin analogs (SSAs) bind to somatostatin receptors and are ...

Journal of Nuclear Medicine December 2025, jnumed.125.270802; DOI: https://doi.org/10.2967/jnumed.125.270802 ...