Affecting roughly half a million Americans each year, bacterial infections caused by Clostridioides difficile—commonly known ...

Researchers at Tufts University School of Medicine are studying C. diff at multiple levels, from how individual bacterial ...

C. diff infections are triggered by two toxins the bacterium produces. Both toxins are difficult to block and prior investigations from the same clinical team have revealed the nature of how they ...

Charles Darkoh, Ph.D., a researcher at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, was recently awarded a five-year, $1.9 million R01 grant by the ...

A novel vaccination approach developed by Vanderbilt Health researchers cleared the harmful gut bacterium Clostridioides difficile (C. diff) in an animal model of infection. An experimental vaccine ...

Fecal microbiota transplantation has become one of the most effective treatments for recurrent Clostridioides difficile infections, but its long-term role in gastroenterology may hinge on moving ...

At the Canadian facility, between Nov. 19, 2013, and March 7, 2015, admitted patients were screened for C. diff toxin B gene with polymerase chain reaction on a rectal swab. Of the 7,599 patients ...

Genetic analysis found that C. diff in an inflamed environment expressed more genes related to carbohydrate and amino acid metabolism. Finally, in vitro experiments demonstrated that C. diff was able ...

Charles Darkoh, Ph.D., a researcher at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health, was recently awarded a five-year, $1.9 million R01 grant by the ...

The presence of antigen-specific and neutralizing antibodies was not associated with Clostridioides difficile infection symptoms, severity, therapy approach, treatment response, or recurrences in a ...

The microbial pathogens of the world have shown us how powerful they can be, most recently proven by the current pandemic virus. Infectious bacteria can be dangerous too, and researchers have been ...

A novel vaccination approach developed by Vanderbilt Health researchers cleared the harmful gut bacterium Clostridioides difficile (C. diff) in an animal model of infection. An experimental vaccine ...