President Donald Trump is pulling the U.S. out of the World Health Organization, raising concerns about the U.N. agency's ability to fight diseases and respond to emergencies around the globe without its biggest funder.

Trump initially removed the U.S. from the WHO in 2020, but Biden reversed his action before it went into effect.

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"Oooh, that's a big one," the newly inaugurated US president said as he approved the document after arriving back at the White House. It was one of dozens of executive actions he put his signature to on day one in office. This marks the second time Trump has ordered the US be pulled out of the WHO.

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Without adequate funding, the African CDC could struggle to respond effectively to health emergencies. He warned that “nations of the world, continents, need to respond positively to this exit of the United States from funding the WHO,” emphasising that Africa, in particular, needs to strengthen its financial commitments to public health.