Symptoms: One of the earliest signs that someone has alkaptonuria is dark stains in their diapers as babies, because the ...

Alkaptonuria is a rare genetic disorder that causes black urine due to homogentisic acid buildup, leading to joint pain, ...

Alkaptonuria (AKU) is a rare genetic disorder characterized by the accumulation of homogentisic acid (HGA) in the body due to a deficiency in the enzyme homogentisate 1,2-dioxygenase. This ...

RA: What is Alkaptonuria and how does it affect patients? OT: Alkaptonuria (AKU) is a rare genetic disease that causes early-onset, severe osteoarthritis. It was discovered more than 100 years ago ...

DelveInsight’s, “HDAC Inhibitor Pipeline Insight” report provides comprehensive insights about 40+ companies and 50+ pipeline ...

TYROSYLURIA, that is, an abnormal excretion of aromatic metabolites of tyrosine, has long been known to occur in human subjects in ascorbic acid deficiency, particularly after a high tyrosine diet ...

LIG4 syndrome is an exceptionally rare disorder caused by a genetic mutation that prevents the body from repairing damaged ...

The rate of sea surface temperature warming has risen from 0.1 degrees Fahrenheit (0.06 degrees Celsius) per decade in the 1980s to 0.5 F (0.27 C) per decade today. The team's modeling suggests ...

The diagnosis of pigmented nail lesions is a concern for both general practitioners and dermatologists, due to the possibility of indicating nail melanoma. The origin of the dark pigmentation can be ...

Service specifications are important in clearly defining the standards of care expected from organisations funded by NHS England to provide specialised care. The specifications have been developed by ...