Ricky Pearsall’s injury status and the ripple effects of major NFL injuries, including Micah Parsons and Patrick Mahomes. Brandon Aiyuk’s dramatic exit and MORE.

By placing Aiyuk on the reserve/left squad list, the 49ers sent the message that they don't need him anymore. And then, to ...

Brock Purdy’s 26-yard run is strangely the 49ers’ longest among 404 carries this peculiarly successful season.

San Francisco 49ers coach Kyle Shanahan has shared some concerning news following the team's win over the Tennessee Titans.

Brandon Aiyuk’s time with the San Francisco 49ers continues to look like it’s all but over. He just had an odd post, too, after coach Kyle Shanahan’s comments about him. Aiyuk hasn’t played football ...

Brandon Aiyuk and the 49ers have apparently kept their relationship long-distance as a divorce inevitably looms.

The most recent move the San Francisco 49ers made involving Brandon Aiyuk suggested he may never suit up for this team again.

“Survivor 48” star Eva Erickson reveals she narrowly avoided Brown University shooting: 'So extremely lucky' Joe Burrow had ...

On Sunday, the 49ers beat Tennessee 37-24, and Aiyuk's replacement, Ricky Pearsall, had six catches for 96 yards. So before ...

The San Francisco 49ers are set to part ways with WR Brandon Aiyuk, and head coach Kyle Shanahan didn't mince words when ...

The Indianapolis Colts host the San Francisco 49ers on " Monday Night Football " in NFL Week 16 action. Both teams are watching injuries in the wake of Week 15 games.

San Francisco 49ers head coach Kyle Shanahan has made a shocking admission about the fallout with Brandon Aiyuk.