Dual pathway blockade targets complement-driven pathology in AChR-positive MG, as well as FcRn-mediated pathogenic IgG recycling. Two patients with refractory anti-acetylcholine receptor (AChR) ...

Between 1970 and 1995, the incidence of new NHL cases increased. Between 2007 and 2016, new cases declined by approximately 0.9% per year, and mortality from NHL decreased by 2.2% per year. 3 ...

Serif’s Modified DNA platform is engineered with carrier molecules and proprietary mRNA cofactors that enhance its activity and expression At the American Society of Gene and Cell Therapy (ASGCT) ...

Regenxbio announced plans to pursue accelerated FDA approval of RGX-202 and prepare for a potential commercial launch in 2027. The pivotal portion of the trial of RGX-202, a gene therapy for Duchenne ...

The trial is running in 142 locations worldwide, including the US, and is expected to be completed in August 2026. The double-blind, placebo-controlled phase 3 study enrolled and randomized 1432 ...

Spesolimab led to rapid defervescence and marked pustule resolution within 2 weeks in a pregnant patient who had failed multiple prior therapies. Spesolimab may be a viable option for pregnant ...

Participants in cohort 1 (aged 6-17 years) demonstrated lower plasma exposure compared with levels previously observed in healthy adult volunteers. The phase 1/2 ELEVATE-44-201 trial evaluating ...

After the enzyme-linked immunosorbent assay was added to the solid phase red cell adherence test, the detection rate of anti-CD36 increased about 15-fold. Platelet antibodies that may lead to fetal ...

In the ADAPT SERON trial, treatment with efgartigimod led to rapid, significant, and sustained improvements in symptoms such as speech, vision, swallowing, and physical function. The US Food and Drug ...

The phase 3 REVEAL study of iodine-124 evuzamitide in 170 adults with suspected cardiac amyloidosis met its primary endpoints of sensitivity and specificity based on visual interpretation. The ...

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