Researchers in the Raman Lab at UW recently published a study discussing sending microbes into space at the International Space Station to evaluate how mutations induced by microgravity may impact ...

DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...

Researchers show that loss of the SPRTN enzyme lets DNA–protein crosslinks accumulate, leak DNA into the cytoplasm, activate ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

DNA, though tightly packed in the nucleus, is constantly threatened by damage from metabolism and external stressors. One particularly severe form of DNA damage is the so-called DNA–protein crosslinks ...

Although DNA is tightly packed and protected within the cell nucleus, it is constantly threatened by damage from normal ...

Notably, inhibition of cGAS-STING from early development rescued mice from developmental lethality and premature aging caused ...

For almost 60 years, scientists have tried to understand why DNA doesn't replicate wildly and uncontrollably every time a cell divides – which they need to do constantly. Without this process, we ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...