The study reports a potential pathway for isoleucine biosynthesis mediated by the underground activity of AHASII, which converts glyoxylate and pyruvate to 2-ketobutyrate. While the findings are ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, public reviews, and a provisional response from the authors. As presented in this ...

Obviously, there cannot be any real pathway holes: accumulation of almost any metabolite which is not converted into a limited number of amino acids, sugars, nucleotides, lipids, and other standard ...

iDepartment of Oral and Maxillofacial Diseases, Head and Neck Center, Cleft Palate and Craniofacial Centre, Department of Plastic Surgery, University of Helsinki and Helsinki University Hospital, ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. RTN4IP1 dysfunction leads to variable ...

Coumarins, a class of metabolites derived from the phenylpropanoid pathway, play critical roles in plant development and interactions with environmental factors. In recent years, numerous studies have ...

Gas chromatography–mass spectrometry (GC–MS) was used to detect the chemical components of natural musk, harvested from forest musk deer at multiple stages of maturity. This research combines ...

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Abstract: Staphylococcus aureus is now being considered under investigation for designing of new inhibitors as the pathogen has acquired resistance against β lactam antibiotics. S. aureus is acquiring ...

The bacterial cell wall or peptidoglycan (PG) is a prime antibiotic target and understanding the cell wall biosynthetic pathway helps to devise new strategies to block bacterial growth. PG consists of ...