San Francisco 49ers quarterback Brock Purdy (13) runs the ball past Tennessee Titans linebacker Cedric Gray, left, during the ...

Amid his best game since returning from a PCL injury, San Francisco 49ers receiver Ricky Pearsall not only reinjured the knee ...

The 49ers received some positive news about left guard Spencer Burford, and are hopeful to get several players back at ...

The San Francisco 49ers hosted a special halftime ceremony on Sunday to celebrate the induction of three-time Super Bowl ...

Two defensive stars were lost for the season. Their QB missed multiple games. Still, here are the 49ers are, a game out of ...

The Tennessee Titans' future lies in the hands of QB Cam Ward, and DT Jeffery Simmons pointed out the most important fact ...

Titans Week 15 inactives include seven San Francisco players ruled out, plus key injury updates and who's active for kickoff.

Just 24 hours before their Week 15 matchup vs. the Tennessee Titans, the San Francisco 49ers got a concerning update on ...

Fans planning to attend the 49ers-Titans Week 15 matchup at Levi’s Stadium on Sunday should prepare for dense fog during the ...

The San Francisco 49ers are bringing up two players from the practice squad for their Week 15 battle with the Tennessee ...

On Saturday, the San Francisco 49ers announced the following roster moves ahead of Sunday's game against the Tennessee Titans ...

The depth of the San Francisco 49ers, especially on defense, is insanely thin. They cannot afford to have a few players or ...