What many women call a “slowing metabolism” is often the metabolic consequence of declining estrogen signaling. This doesn’t mean hormones are the only factor. Nutrition, strength training, sleep, stress, and overall lifestyle still matter enormously. But understanding the biology helps explain why so many women feel like their bodies changed the rules during perimenopause and menopause. This is also one reason I’ve become fascinated by the growing research on the interaction between estrogen an

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