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Antidepressants for Anxiety: Sertraline (Zoloft) Dosing, Timeline & Why It’s Used for GAD GAD case: insomnia, muscle tension, GI issues. We start sertraline (Zoloft) low (25–50 mg) and titrate based on symptoms. Key points: SSRIs aren’t fast-acting—expect 4–6+ weeks per dose for maximal benefit; daily adherence matters ...
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